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We studied the effect of the carbonic anhydrase inhibitor acetazolamide on 24 patients with essential tremor by patient self-evaluation of functional disability,rating of motor task function,and clinical rating of tremor severity.Acetazolamide significantly reduced tremor severity,but there was no statistically significant change in patient self-assessment of function or motor task rating.Although side effects were common,over half the patients elected to remain on the drug. |
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